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Phenylethylamine (PEA)

Also called beta-phenylethylamine, phenethylamine

What Huberman said

Huberman says PEA gives a sharp but very transient dopamine increase (about 30 to 45 minutes) and that he takes it from time to time, around 500 mg and often with 300 mg alpha-GPC, before intense work bouts. His stance moved from not having tried it (March 2021) to using 300 to 600 mg (2022) and, in January 2023, saying he relies on PEA rather than L-tyrosine for dopamine augmentation.

Doses, as he worded them

  • “500 milligrams of PEA”[3]

    with 300 mg alpha-GPC before intense bouts of work

  • “about 300 to 600 milligrams”[4]

    with some L-tyrosine, or on its own with alpha-GPC (2022)

  • “500 milligrams of phenylethylamine”[5]

    swapped in for L-tyrosine every once in a while (2022)

Quoted, not prescribed. Talk to a doctor or pharmacist first if you take medication, are pregnant or have a health condition.

Cautions he mentions

  • Don't take these after 2-3 p.m. if you intend to sleep that night.[1]
  • If you have bipolar depression or any other dopamine-sensitive condition, be very cautious.[1]
  • Check with your healthcare provider before you take anything or remove anything.[6]

Where he said it

  1. 1
    “Note: Don't take these after 2-3 p.m. if you intend to sleep that night.”

    Tools to Manage Dopamine and Improve Motivation & Drive

    Newsletter · 2022

    Read the newsletter
  2. 2
    “I rely on something else for dopamine augmentation, which is phenylethylamine, which is a little bit more short-lasting.”

    Developing a Rational Approach to Supplementation for Health & Performance

    Episode · 01:38:55 · 2023

    Watch from 01:38:55Episode page
  3. 3
    “I will take 500 milligrams of PEA, and I'll take 300 milligrams of alpha-GPC.”

    Essentials: Controlling Your Dopamine for Motivation, Focus & Satisfaction

    Episode · 00:27:48 · 2025

    Watch from 00:27:48Episode page
  4. 4
    “I'll take phenylethylamine at dosages of about 300 to 600 milligrams along with some L-tyrosine,”

    Optimize & Control Your Brain Chemistry to Improve Health & Performance

    Episode · 01:10:59 · 2022

    Watch from 01:10:59Episode page
  5. 5
    “every once in a while, I'll swap out L-tyrosine and put in 500 milligrams of phenylethylamine”

    Focus Toolkit: Tools to Improve Your Focus & Concentration

    Episode · 01:42:56 · 2022

    Watch from 01:42:56Episode page
  6. 6
    “I actually haven't tried it before, so I can't report on my own experiences.”

    How to Increase Motivation & Drive

    Episode · 00:58:00 · 2021

    Watch from 00:58:00Episode page

Part of his stacks

Related

This page reports what Andrew Huberman has said. It isn’t medical advice and NSDR.co isn’t affiliated with Huberman Lab. Talk to a doctor or pharmacist first if you take medication, are pregnant or have a health condition. Safety information